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William Thode Ocular Microbiology Laboratory

Anne Bates Leach Eye Center Clinical Microbiology Laboratory

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Investigator / Contact Person Darlene Miller, DHSc, MPH, CIC, FARVO


  • Epidemiology and pathology of ocular infectious diseases.
  • Emerging antimicrobial resistance and  novel treatment outcomes.
  • Role of  microbial toxins  on the immune response and pathology and treatment outcomes of ocular infections.
  • Diversity of the ocular microbiome in health and disease.
  • Mechanism of interspecies signaling in ocular infections.
  • Role of Infection Control and Prevention in reducing ocular infections and antimicrobial resistance.
  • Implementation  of  “artificial intelligence” and “omics” technology for rapid detection of ocular pathogens and metabolic pathways in ocular surface homeostasis and dysbiosis.
  • Maintenance of the BPEI Ocular Pathogen Biobank