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Mitochondrial Physiology Laboratory

Ophthalmic Mitochondrial Bioenergetics Center

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Investigator / Contact Person Anh Pham, M.D., Ph.D.

Research Focus

The Mitochondrial Physiology Laboratory is focused on measuring and improving mitochondrial health in models of optic neuropathy using a multi-modal approach. We develop murine models to enable high-resolution imaging analysis for quantifying mitochondrial clearance and dynamics in primary tissues, organotypic cultures, and retinal explants. We are exploring innovative methodologies to edit mitochondrial DNA using CRISPR-based technology.

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