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Funding Opportunities

The Intramural Funding Program (IFP) enables Sylvester Comprehensive Cancer Center to advance its mission to reduce the burden of cancer in its catchment area by supporting strategically aligned innovative research. IFP funds, which come from the CCSG, the State of Florida, the University of Miami, and philanthropy, facilitate impactful collaborations, advance transdisciplinary, translational, and team science research and accelerate clinical trial development. The program’s success is measured by the generation of peer reviewed funding, publications, patent applications, and externally funded clinical trials.

Sylvester’s IFP, is overseen by the Deputy Director, Dr. Antonio Iavarone, M.D. and a team which uses well-established, rigorous processes for soliciting, reviewing, awarding, and tracking research outcomes. For questions about the IFP please contact:

Application and Award Announcement Dates

Cycle I Cycle II Cycle III
Application Due Dates February August October
Scientific Merit Review March- April September-October October
Award Selection Meeting April October October
Earliest Project Start Date July December November

Review the specific request for applications (RFA) for deadline information. Not all RFAs are available in all cycles.

IFP Award Categories

For the full-text RFAs and to apply please visit our Sylvester InfoReady site:

Transdisciplinary Science Pilot Award

The purpose of this funding opportunity is to encourage investigators from different disciplines to collaborate on impactful research that addresses priority cancers, advances Sylvester’s CA-relevant research portfolio, develops new methodologies for tackling difficult and complex cancer problems, and advances novel therapeutic approaches.

Translational Science Pilot Award

This award supports novel translational research projects that 1) align with Sylvester’s Strategic Plan; 2) have the capability to be developed into an IIS; and 3) include correlative studies that examine therapeutic resistance (or response) to further the development of potential biomarkers.

Community Outreach and Engagement Pilot Award

This funding mechanism promotes transdisciplinary research collaborations focused on cancer disparities, that address issues relevant to the diverse community of people living in South Florida. Pilot funds allow investigators to pursue new ideas and develop preliminary data to support successful NCI or cancer-related NIH R01 applications.

Early Career Advancement Pilot Award

The purpose of this new funding opportunity is to enhance the diversity of Sylvester’s cancer research workforce by supporting early career investigators from underrepresented minorities populations in the sciences. In alignment with Sylvester’s 2019-2023 Strategic Plan and the Plan to Enhance Diversity (PED), this mechanism provides pilot funds to junior investigators who have no current peer-reviewed funding, with the goals of attracting them into cancer research and serving as a catalyst for the submission of extramural cancer research grants.

Diversity, Equity & Inclusion Recognition Supplement Award

This supplemental funding opportunity recognizes an individual or group with an active research project or a peer-reviewed grant proposal under review that promotes health equity, addresses and/or mitigates cancer disparities, and advocates for and/or enhances diversity, equity, and inclusion at the Cancer Center.

Team Science Award

This funding mechanism supports groups of investigators working as part of a multidisciplinary research team that plans on submitting a large cancer-related multi-PI grant (e.g., P01, SPORE) within one to two years of the award.

NCI/NIH Boost Award

This award provides supplemental funding to recently awarded NCI/NIH awards. It is designed to restore the budgets of funded proposals, which allows the research to proceed at its intended pace. Over time, these funds should lead to higher rates of successful NCI/NIH grant renewals and other awards.

NCI/NIH Catalyst Award

This award promotes the successful resubmission of NIH/NCI applications that have received nearly fundable scores from an NIH study section. Awards are given to investigators upon receipt of the percentile ranking of the Cancer Center member’s grant application. Recipients of these awards are required to resubmit a revised application within one year of notification that the initial grant application was not funded.

Sylvester Bridge Funding Award

This funding mechanism assists Cancer Center members in maintaining their research activities in the event of a lapse in extramural funding based on their needs over a one-year period. Applicants must have applied or be applying for continuation of extramural funding for the application to be eligible.

Clinical Trial Acceleration Award

The goal of this funding mechanism is to support highly innovative and programmatically important investigator-initiated, national, or industry-sponsored clinical trials, as well as innovative translational studies that have the promise of leading to new clinical trial concepts. The funding opportunity includes three categories: (1) Investigator Initiated Studies (IIS) focused on innovative, multi-disciplinary projects; (2) Gap Funding (GAP) for treatment trials that have a gap between sponsor funding and the SCCC budget estimate; and (3) Translational Funding (TRL) for correlative studies linked to a clinical trial and/or which have promise of being the foundation for an IIS. Prioritization will be given to trials which are catchment area relevant, programmatically aligned or led by a junior faculty.

Engineering Cancer CuresTM Pilot Award

Engineering Cancer Cures is a joint initiative of the College of Engineering and Sylvester Comprehensive Cancer Center with a mission to develop and deploy innovative engineering technologies for cancer prevention, detection, diagnosis, and treatment. These awards support novel collaborative efforts, involving one member from the College of Engineering and generally one from the Miller School.

FACCA Pilot Awards

The purpose of this Florida Academic Cancer Center Alliance (FACCA) Funding Opportunity is to support scientific collaborations across three Florida cancer centers – Sylvester Comprehensive Cancer Center, Moffitt Cancer Center and UF Health Cancer Center. Focus areas are Cancer & Aging, Cancer Prevention, Care Delivery & Survivorship, Metabolism, Tumor Immunology and Immunotherapy and Infection and Cancer.

American Cancer Society (ACS) Institutional Research Grant (IRG) Pilot Awards

This competition is the result of an ACS Institutional Research Grant to the University of Miami whose purpose is to support early career faculty and encourage independent cancer research. This funding provides “seed money” to early-career investigators who have no current peer-reviewed research grant support, with the goals of encouraging cancer research and servicing as a catalyst for the submission of national research grants.


For the full-text RFAs and to apply please visit our Sylvester InfoReady site: CLICK HERE

While most funding mechanisms require that the applicant be a Sylvester member or be working with a Sylvester member, two mechanisms do not: 1) The American Cancer Society Institutional Research Grant (ACS-IRG) specifies that applicants cannot have received any peer-reviewed funding, thus they are unlikely to be Sylvester members. 2) Sylvester’s Early Career Advancement Award seeks to support a broad base of underrepresented minority (URM) populations engaged in cancer research regardless of membership status. For all mechanisms, the proposed project must be cancer-related, CA-relevant and cannot overlap with the applicant’s existing funded projects.

For the full-text RFAs and to apply please visit our Sylvester InfoReady site:

For more information, please contact us at SylvesterIFP@med.miami.edu.