Research Focus
La Tessa’s lab focuses on pioneering research to improve the precision and effectiveness of proton therapy. This radiation modality has emerged as an attractive alternative for cancer treatment because of the superior spatial dose distribution in the patient compared to conventional photon therapy. Proton unique characteristic translates into a lower radiation exposure of normal tissue surrounding the tumor, and thus leads to a reduced incidence of side effects. By integrating expertise from nuclear physics, applied mathematics, and cell biology, the lab investigates the fundamental mechanisms that drive the biological response to proton radiation, and works to translate the insights into improved clinical practice.
Our team combines cutting-edge experimental techniques with advanced instrumentation, including microdosimetry and radiation detectors, to achieve high-resolution characterization of radiation effects at the cellular and subcellular levels. We leverage powerful Monte Carlo simulation tools—such as GEANT4, PHITS, and TOPAS—alongside radiobiological modeling and machine learning to optimize treatment planning and predict patient-specific outcomes.
Through this multidisciplinary approach, the La Tessa Lab aims to develop more personalized and effective proton therapy strategies, with the ultimate goal of improving cancer care and reducing treatment-related side effects.
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