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Cancer Proteomics Shared Resource
« Back to Cancer Proteomics Shared Resource
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The Cancer Proteomics Shared Resource is equipped with advanced mass spectrometry platforms and supporting infrastructure and software to enable high‑quality proteomic analysis.

Mass Spectrometry

  • Thermo Scientific Orbitrap Ascend tribrid mass spectrometer with FAIMS and nESI source with Thermo Scientific Vanquish UHPLC
  • Thermo Scientific Orbitrap Astral Zoom mass spectrometer with nESI source and Thermo Scientific Vanquish UHPLC

Software

  • Proteome Discoverer with Chimerys + Ardia Server for DIA search
  • MS Amanda, Sequest HT, and Comet for DDA search
  • XlinkX for cross-link search
  • MaxQuant for SILAC search

Workstations

  • Dell Precision 7865 workstation with AMD Ryzen Threadripper PRO 7985WX (64 cores, 128 threads, 256 GB memory)
  • Dell Precision 7865 workstation with AMD Ryzen Threadripper PRO 5995WX (64 cores, 128 threads, 256 GB memory)
    Thermo Scientific Ardia Server (96 TB RAID6)

Acronyms

  • FAIMS: high-field asymmetric waveform ion mobility spectrometry
  • nESI: nano-electrospray ionization
  • UHPLC: ultra-high performance liquid chromatography
  • SILAC: stable isotope labeling by amino acids in cell culture
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